Melatonin

Introduction
Melatonin—chemically known as N-acetyl-5-methoxytryptamine—is an indole-based hormone widely found in animals, plants, and microorganisms. In the human body, it is primarily secreted by the pineal gland; its secretion exhibits a distinct circadian rhythm, increasing significantly at night while being suppressed during the day. Melatonin plays a pivotal role in regulating the body’s circadian rhythms, improving sleep quality, mitigating oxidative stress, and modulating immune function.

Physiological Functions
 Regulation of Circadian Rhythms
Melatonin serves as a key signaling molecule for maintaining the body’s “biological clock.” Light signals are transmitted from the retina to the suprachiasmatic nucleus (SCN), where they inhibit melatonin secretion. Conversely, as the environment darkens, melatonin begins to be released in large quantities, inducing natural drowsiness and thereby helping to establish a regular sleep-wake cycle.

  Induction of Sleep
Melatonin helps shorten sleep latency (the time it takes to fall asleep), reduce the frequency of nocturnal awakenings, and increase the duration of deep sleep. It is primarily indicated for sleep disorders resulting from circadian rhythm disruptions—for instance, effectively alleviating jet lag associated with long-distance travel.

  Antioxidant Activity
Melatonin is recognized as one of the most potent endogenous antioxidants. It effectively scavenges free radicals; unlike many other antioxidants, melatonin is both water-soluble and lipid-soluble, allowing it to readily enter every cell in the body—including mitochondria and the nucleus—to provide comprehensive antioxidant protection for DNA.

  Immune Modulation
Melatonin exerts a dual-modulatory effect on the immune system. At physiological concentrations, it promotes the proliferation of T lymphocytes and the production of cytokines, thereby enhancing the body’s overall resistance. In the context of certain inflammatory responses, melatonin can mitigate tissue damage by suppressing excessive immune reactions.

Advantages
1. High Purity, Compliant with Pharmacopoeia Standards: The melatonin content of the product exceeds 99% (determined via HPLC).
2. Stable Product Quality: Ensured by a stable and timely global supply chain, with quality control measures implemented throughout the entire process—from raw materials to the finished product.
3. Flexible Customization, Adaptable to Various Formulations: Compound formulations can be developed according to specific requirements, offering synergistic effects when combined with ingredients such as GABA, L-theanine, and chamomile extract.

Recommended Plant-Derived Sleep-Aid Ingredients
· Chamomile Extract
· Zizyphus Seed Extract
· Valeriana Officinalis Extract
· L-Theanine

Packing & Storage
Pack in paper-drums and two plastic-bags inside. Net Weight: 25kgs/paper-drum.
1kg-5kgs plastic bag inside with aluminum foil bag outside. Net Weight: 20kgs-25kgs/paper-drum.
Store in a well-closed container away from moisture and light.

Shelf Life
2 years if sealed and store away from direct sun light.

Natural Ingredients, Healthy Life.
Finca Farm is a botanical/plant extracts manufacturer and Natural Ingredient Solutions provider.
Please feel free to contact us for your any concerns.